Comparative Analysis of Temperature-Controlled Cryotherapy Versus Intralesional Triamcinolone Acetonide Injection for Alopecia Areata: An Intrasubject Split-Lesion Pilot Study

    Hanjae Lee, J.W. Lee, S K Park … Oh Sang Kwon
    Studysummary In this pilot study, cryotherapy using a device that precisely controls cooling duration improved hair regrowth for patchy alopecia areata when applied for 20 seconds with two freeze-thaw cycles, similar to standard triamcinolone acetonide injections, but not when applied for 10 seconds.
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    Research cited in this study 3

    1. Cold Shock Therapy Promotes Hair Growth in Association with Upregulation of Cold-Inducible RNA-Binding Protein and Vascular Endothelial Growth Factor Journal of Dermatological Science · 2024
    2. Efficacy and Safety of Superficial Cryotherapy for Alopecia Areata: A Retrospective Comprehensive Review of 353 Cases Over 22 Years The Journal of Dermatology · 2016
    3. Benefit of Different Concentrations of Intralesional Triamcinolone Acetonide in Alopecia Areata: An Intrasubject Pilot Study Journal of the American Academy of Dermatology · 2015

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