Exploring the New Horizons of Drug Repurposing: A Vital Tool for Turning Hard Work into Smart Work

August 2019 in “ European Journal of Medicinal Chemistry ”

Rajesh Kumar, Seetha Harilal, Sheeba Varghese Gupta, Jobin Jose, Della Grace Thomas Parambi, Md. Sahab Uddin, Muhammad Ajmal Shah, Bijo Mathew

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research Evaluation and Treatment of Hirsutism in Premenopausal Women

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This guideline discusses the evaluation and treatment of hirsutism in premenopausal women, recommending oral contraceptive pills or antiandrogens as initial therapies with weak support from low-quality evidence.

research Repurposing of Approved Cardiovascular Drugs

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This review discusses the drug repurposing of cardiovascular medications like aspirin and statins for new uses, including potential anti-tumor effects, noting promising experimental outcomes but less conclusive clinical trials, particularly in the field of cancer treatment.

research DrugNet: Network-Based Drug–Disease Prioritization by Integrating Heterogeneous Data

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This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.

research Medication Repurposing: New Uses for Old Drugs

6 citations , May 2011 in “Journal of Pharmacy Technology”

This article discusses the growing trend of repurposing existing medications for innovative therapeutic uses and highlights the need for pharmacy practitioners to be informed about accessing clinical evidence related to these applications, but it reports no new results.

research Bimatoprost in the Treatment of Eyelash Hypotrichosis

69 citations , April 2010 in “Clinical ophthalmology”

This article reviews the use of bimatoprost for eyelash hypotrichosis and reports its effectiveness in promoting eyelash growth but highlights uncertain efficacy in cases of eyelash alopecia areata.

research Hypertrichosis of the Eyelashes Caused by Bimatoprost

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A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.

research Topical Minoxidil in Early Male Pattern Baldness

138 citations , August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

research Alopecia Areata Treated With Topical Minoxidil

78 citations , April 1984 in “Archives of Dermatology”

This study found that 1% minoxidil topical solution led to terminal hair regrowth in some patients with alopecia areata, though it was only cosmetically acceptable in less than half of those cases.

research Minoxidil

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Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.