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    Spironolactone for Female Acne: A Meta-Analysis of Safety and Efficacy

    July 2024
    Ali Mohammad Aleid, Wafa A Alrezqi, Dana Omar Al Mushayt … Batil Alonazi
    Studysummary This research review found that spironolactone can significantly improve acne severity more effectively than a placebo, with 73.3% of patients reporting satisfaction despite a 26.7% rate of adverse events among the 1,548 participants studied.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 4

    1. High-Dose Spironolactone for Acne in Patients with Polycystic Ovarian Syndrome: A Single-Institution Retrospective Study Journal of The American Academy of Dermatology · 2019
    2. Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study Dermatology · 2017
    3. The Effect of Spironolactone on Genital Skin 5α-Reductase Activity Journal of steroid biochemistry/Journal of Steroid Biochemistry · 1985
    4. Interaction of Spironolactone with Rat Skin Androgen Receptor Canadian journal of biochemistry · 1979

    Related research 2

    1. Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study Dermatology · 2017
    2. Lack of Effect of Spironolactone on Hair Shaft Diameter in Hirsute Females Postgraduate medical journal · 1989