Calcium, Cobalt, Strontium, and Cerium-Based Binary Silicate Bioactive Nanoglasses: Rational Comparison in Bioactive Properties for Optimizing Tissue Repair Applications

January 2026 in “ Regenerative Biomaterials ”

Yanzi Zhao, Jing Tian, Liuyang Zhang, Long Zhang, Qian Huang, Xiaoyan Qu, Bo Lei

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calcium cobalt strontium cerium bioactive glass nanoparticles apatite nucleation anti-inflammatory effects antioxidant activity angiogenesis wound closure vasculature hair follicle restoration hair-follicle regeneration

Studysummary This study synthesized and compared single-ion doped silicate bioactive glass nanoparticles for tissue repair, finding that BSr and BCe were most effective in accelerating wound healing and restoring vasculature, with BSr particularly reducing inflammation and BCo enhancing hair follicle regeneration but with limited biosafety window.

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