Attenuated PER3 Amplitude in Hair Follicles Is Associated With Sleep Irregularity in Schizophrenia

    July 2026 in “ Translational Psychiatry ”
    Mikkel Iwanoff Kolind, Rikke Kruse, Jan C. Brønd … Claus B. Juhl
    Studysummary This study found that individuals with both schizophrenia and obesity showed reduced PER3 gene expression amplitude and lower melatonin levels compared to normal-weight controls, suggesting dampened circadian rhythms linked to irregular sleep. Hair follicle sampling was effective for assessing these molecular rhythms.
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