Physiological Function of Krox20 (Egr2) in Epithelial Stem Cells

April 2021 in “ Journal of Investigative Dermatology ”

Edem Tchegnon, Chengheng Liao, Elnaz Ghotbi, Asal Saeid, Jenny Raman, Lu Q. Le

Krox20 Egr2 epithelial stem cells hair follicles keratinocytes hair shaft formation melanocyte differentiation hair pigmentation epidermal differentiation epidermal stem cell markers apoptosis Notch pathway Wnt/βcatenin pathway epidermal homeostasis stem cell population maintenance hair loss stem cells skin cells hair growth cell survival cell differentiation

Studysummary Krox20 is crucial for hair growth and maintaining skin stem cells.

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