Case Report: Paired Vertex-Occipital Assessment Reveals Donor-Area Involvement in Diffuse Unpatterned Alopecia

    March 2026 in “ Frontiers in Medicine ”
    Yonglong Xu, Huaiwei Liu, Ying Xie … Dingquan Yang
    Studysummary This study reported that two male patients with diffuse unpatterned alopecia exhibited donor-area involvement in both the vertex and occiput, challenging the assumption of occipital stability for hair transplantation, and showed partial improvement following treatment with oral finasteride and topical minoxidil.
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    Research cited in this study 7

    1. Causes and Therapeutic Limitations of Clinical Alopecia and the Advent of Human Pluripotent Stem Cell Follicular Transplantation Stem Cell Research & Therapy · 2025
    2. Hair Transplantation: State of the Art Dermatologic Surgery · 2025
    3. Efficacy of Thermus Thermophilus Fermentation Extract in Promoting Hair Growth and Improving Scalp Health in Androgenic Alopecia: A Clinical and In Vitro Study Journal of Cosmetic Dermatology · 2025
    4. Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia Scientific Reports · 2023
    5. Hair Transplantation: Basic Overview Journal of The American Academy of Dermatology · 2021
    6. Female Pattern Hair Loss in Men: A Distinct Clinical Variant of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2020
    7. Female Androgenetic Alopecia: An Update on Diagnosis and Management American Journal of Clinical Dermatology · 2019