Molecular Signaling in Feather Morphogenesis

October 2006 in “ Current opinion in cell biology ”

Chih‐Min Lin, Ting Jiang, Randall B. Widelitz, Cheng‐Ming Chuong

Studysummary This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.

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7 / 7 results

research Distinct Mechanisms Underlie Pattern Formation in the Skin and Skin Appendages

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This article discusses various skin pattern formations, their molecular mechanisms, and highlights the need for further understanding to connect molecular biology with organism phenotypes, without providing new clinical findings.

research Expression of Hex During Feather Bud Development

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This study found that Hex gene expression patterns in chick embryo dorsal skin during feather bud development suggest a significant role in initiating feather morphogenesis.

research CDermo-1 Misexpression Induces Dense Dermis, Feathers, and Scales

29 citations , December 2004 in “Developmental biology”

In this study, forced expression of the transcription factor cDermo-1 in chicken dermis led to the formation of ectopic feather buds and enhanced feather growth, demonstrating its role in initiating skin appendage development.

research Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common?

23 citations , December 2004 in “Differentiation”

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research FGF Signaling Is Required for Initiation of Feather Placode Development

66 citations , June 2004 in “Development”

This study found that FGF signaling is necessary for the initiation of feather placode development in chicken embryos, with FGF10 being implicated as an early dermal signal in the process.

research Integument Pattern Formation Involves Genetic and Epigenetic Controls: Feather Arrays Simulated by Digital Hormone Models

112 citations , January 2004 in “The International journal of developmental biology”

This study found that feather patterning is primarily self-organizing and dynamic, relying on both genetic and epigenetic controls, with implications for similar processes like fingerprints and pigmentation.

research Shift of Localized Growth Zones Contributes to Skin Appendage Morphogenesis: Role of the Wnt/β-Catenin Pathway

75 citations , January 2003 in “Journal of Investigative Dermatology”