Investigating the Role of Notch Ligands Regulating Epidermal Stem Cell Differentiation

January 2025 in “ eScholarship@McGill (McGill) ”

Nathan, Vandana

Notch ligand Jag2 epidermal stem cell differentiation Hes1 basal epidermal stem cells melanocyte morphology UV rays basal layer hyperplasia epidermal differentiation homeostasis

Studysummary In this study, loss of the Notch ligand Jag2 in mouse epidermal cells disrupted early differentiation and affected the structure and behavior of adjacent melanocytes, highlighting Jag2's role in epidermal differentiation and tissue homeostasis.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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