Nrf2-Mediated Expansion of Pilosebaceous Cells Accelerates Cutaneous Wound Healing

December 2018 in “ The American journal of pathology ”

Sukalp Muzumdar, Hayley Hiebert, Eric Haertel, Maya Ben‐Yehuda Greenwald, Wilhelm Bloch, Sabine Werner, Matthias Schäfer

Nrf2 keratinocytes pilosebaceous cells epigen epidermal growth factor receptor wound healing re-epithelialization EGFR

Studysummary This study found that genetic activation of Nrf2 in keratinocytes accelerates wound repair by enhancing cell proliferation and re-epithelialization, suggesting potential use for Nrf2-activating compounds in individuals with impaired healing.

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research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge

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