Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration
August 2011
in “
Journal of Controlled Release
”
genetically-manipulated adult stem cells epidermis hair follicles bone marrow adipose tissue re-epithelialization differentiation revascularization collagen gene expression repigmentation hair follicle neogenesis adipose-derived stem cells dermal fibroblast proliferation collagen synthesis angiogenesis immunomodulatory effects bone marrow-derived stem cells epidermis derived stem cells hair follicle-derived stem cells gene delivery viral vectors non-viral vectors liposome vectors regenerative medicine ADSCs BMSCs ESCs HFSCs
Studysummary This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.
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