Pattern Alopecia During Hormonal Anticancer Therapy in Patients with Breast Cancer

    January 2014 in “ Annals of Dermatology ”
    Jin Park, Ju Ik Kim, Seok Kweon Yun … Chull Wan Ihm
    Studysummary In this report, five female patients undergoing hormonal anticancer therapy for breast cancer prevention developed pattern alopecia, which the authors attribute to androgen-estrogen imbalance caused by antiestrogenic drugs.
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    Research cited in this study 7

    1. Finasteride and Male Breast Cancer: Does the MHRA Report Show a Link? PubMed · 2010
    2. Drug Reactions Affecting Hair: Diagnosis Dermatologic Clinics · 2007
    3. Alopecia in a Premenopausal Breast Cancer Woman Treated with Letrozole and Triptorelin Annals of Oncology · 2003
    4. 17α-Estradiol Induces Aromatase Activity in Intact Human Anagen Hair Follicles Ex Vivo Experimental Dermatology · 2002
    5. Tamoxifen-Induced Total Alopecia Annals of Internal Medicine · 2001
    6. Tamoxifen-Induced Female Androgenetic Alopecia in a Patient with Breast Cancer Annals of Internal Medicine · 1997
    7. Estrogen-Androgen Imbalance in Patients with Hirsutism and Amenorrhea The Journal of Clinical Endocrinology & Metabolism · 1974