Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

    August 2008 in “ American Journal Of Pathology
    Peter M. Elias, Jack L. Arbiser, Barbara E. Brown, Heidemarie Rossiter, Mao‐Qiang Man, Francesca Cerimele, Debra Crumrine, Roshan Gunathilake, Eung Ho Choi, Yoshikazu Uchida, Erwin Tschachler, Kenneth R. Feingold
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    Studysummary This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.
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