Vitamin D Receptor Gene Polymorphisms Are Not Associated With Alopecia Areata

September 2007 in “ International Journal of Dermatology ”

Ahmet Rüçhan Akar, Funda Orkunoglu, Mustafa Tunca, Halis Bülent Taştan, Zafer Kurumlu

vitamin D receptor VDR gene polymorphisms BsmI ApaI TaqI alopecia areata AA

Studysummary This study suggests no significant association between vitamin D receptor gene polymorphisms and alopecia areata.

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The study investigated the association between vitamin D receptor (VDR) gene polymorphisms (BsmI, ApaI, and TaqI) and alopecia areata (AA) by genotyping 32 patients with AA and 27 healthy controls. The allele and genotype frequencies for the B, A, and T polymorphisms showed no statistically significant differences between the patient and control groups. The findings suggested that VDR gene polymorphisms were not associated with alopecia areata.

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