The Blastema and Epimorphic Regeneration in Mammals
December 2017
in “
Developmental Biology
”
Studysummary This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
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