85 citations
,
December 2017 in “Developmental Biology” This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
39 citations
,
April 2015 in “Regeneration” This review discusses the regenerative processes of lizard tails, particularly focusing on the diversity in blastema development across different species, and reports no new findings.
46 citations
,
March 2015 in “Regeneration” This review revisits the mechanisms of wound induced hair follicle neogenesis in mice and concludes that the process involves canonical WNT signaling activated by Fgf9 from γδ T cells, but more research is needed to fully understand its cellular bases.
10 citations
,
October 2016 in “Experimental Dermatology” This essay discusses the role of the nail in mammalian digit tip regeneration and explores whether nail stem cells are solely responsible for this regenerative ability, with no new results presented.
1 citations
,
November 2017 This chapter reviews classic regeneration models in planarian worms and amphibian limbs, focusing on the role of stem cells, and reports no new experimental results.