Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors

    July 2016 in “ Radiation Research ”
    Aviram Mizrachi, Ana P. Cotrim, Nora Katabi … Adriana Haimovitz‐Friedman
    Studysummary This study found that radiation-induced salivary gland dysfunction in mice involves microvascular damage mediated by ceramide and reactive oxygen species, suggesting ROS scavengers could protect salivary function during radiotherapy for head and neck cancer.
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