Serum-Based Assessment of Alopecia Areata Response to Treatment Using ATR-FTIR Spectroscopy

    May 2025 in “ Diagnostics ”
    Charlotte Delrue, Arno Belpaire, Sigurd Delanghe … Reinhart Speeckaert
    Studysummary This study found that ATR-FTIR spectroscopy combined with machine learning effectively differentiated alopecia areata patients from healthy controls with an AUC of 0.85, and also showed promise in predicting treatment response, particularly through alterations in the Amide I band.
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    Research cited in this study 5

    1. Visualizing Severity Of Alopecia Tool Scores In The Clinical Setting Using Patient Images From A Clinical Trial JEADV clinical practice · 2024
    2. Biomarkers in Alopecia Areata: A Systematic Review and Meta-Analysis Autoimmunity reviews · 2023
    3. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    4. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015
    5. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013

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