Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial on 225 Subjects

This study assessed the impact of a novel dietary supplement, AGA-P, on enhancing the efficacy of pharmacological treatments for androgenic alopecia (AGA) in a 6-month trial with 225 subjects. The supplement, containing Serenoa repens, Cucurbita pepo, L-Cystine, and Vitamin C, was tested alongside standard treatments like minoxidil and finasteride. Results indicated that 36.5% of participants in the supplement group achieved significant improvement in hair density compared to 24% in the control group, with the difference being statistically significant (p=0.0428). The supplement was well tolerated with minimal side effects, suggesting it could be a beneficial adjunctive treatment for AGA, although further research is needed due to the trial's limitations.