Rapid Formation of Multicellular Spheroids in Double-Emulsion Droplets with Controllable Microenvironment

December 2013 in “ Scientific Reports ”

Hon Fai Chan, Ying Zhang, Yi‐Ping Ho, Ya‐Ling Chiu, Youngmee Jung, Kam W. Leong

Studysummary In this study, researchers developed a microfluidics-based method for creating uniform, size-controlled stem cell spheroids that enhance osteogenic differentiation when encapsulated in alginate-RGD microgels.

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Scalable Production of Controllable Dermal Papilla Spheroids on PVA Surfaces and the Effects of Spheroid Size on Hair Follicle Regeneration

research Scalable Production of Controllable Dermal Papilla Spheroids on PVA Surfaces and the Effects of Spheroid Size on Hair Follicle Regeneration

78 citations , October 2012 in “Biomaterials”

This study found that both human and rat dermal papilla spheroids can induce hair follicle neogenesis, but larger spheroids increase inductivity without significantly affecting hair fiber diameter.