Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars

    February 2016 in “ British journal of pharmacology ”
    Xiaozhi Bai, Jiaqi Liu, Longlong Yang … Dahai Hu
    Studysummary This study found that SIRT1 negatively regulates fibroblast activation and excessive scar formation, suggesting it may be a promising drug target for treating hypertrophic scars.
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    Research cited in this study 1

    1. Cutaneous Scarring: Pathophysiology, Molecular Mechanisms, and Scar Reduction Therapeutics Journal of the American Academy of Dermatology · 2011