Improved Humoral Immunity and Protection Against Influenza Virus Infection With a 3D Porous Biomaterial Vaccine

    Hiromi Miwa, Olivia Q Antao, Kindra M. Kelly-Scumpia … Dino Di Carlo

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study reported that an injectable hydrogel microparticle vaccine platform enhanced antibody responses and protection against influenza in mice, outperforming the traditional adjuvant aluminum hydroxide.
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    Research cited in this study 2

    1. Engineering Immunomodulatory Biomaterials to Drive Skin Wounds Toward Regenerative Healing Cold Spring Harbor Perspectives in Biology · 2022
    2. Activating an Adaptive Immune Response from a Hydrogel Scaffold Imparts Regenerative Wound Healing Nature Materials · 2020