17927 A pilot study of intrascalp platelet-rich plasma injections for hair loss in Nigerian patients
December 2020
in “Journal of The American Academy of Dermatology”
TLDR The conclusion is that many small genetic variations influence claw disorders in cows, and using genomic selection could help reduce these disorders.
The document presents a genome-wide association study (GWAS) on claw disorders and trimming status in dairy cattle, involving data from 20,474 cows for claw disorders and 50,238 cows for trimming status. The study identified 10 significant and 45 suggestive single nucleotide polymorphisms (SNPs) associated with claw disorders, mainly located on Bovine chromosome 8 (BTA8). Three of these suggestive SNPs were validated in a separate dataset of 185 bulls. No significant or suggestive SNP associations were found for infectious claw disorders, sole hemorrhage, and white line separation. For trimming status, one significant and one suggestive SNP were detected on BTA15. The study concluded that many SNPs, each explaining a small proportion of the genetic variance, influence claw disorders, suggesting that genomic selection could be a promising approach to reduce the incidence of claw disorders by breeding.
View this study on jaad.org →
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