Driving Drugs Deeper: Force-Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

    August 2026 in “ Small ”
    Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh
    Studysummary This review discusses the potential of force-driven microneedles for active and rapid transdermal delivery of therapeutic agents but reports no new experimental results.
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    Research cited in this study 4

    1. Optimizing Therapeutic Delivery of Microneedles Through Gas-Propelled Technology Therapeutic Delivery · 2025
    2. Microneedle-Mediated Hypoxic Extracellular Vesicle-Encapsulated Selenium Nanoparticles Delivery to Treat Androgenetic Alopecia Journal of Controlled Release · 2025
    3. Emerging Smart Microneedle Technologies in Psoriasis: Convergence of Nanocarriers, Machine Learning, and Personalized Delivery RSC Pharmaceutics · 2025
    4. Platinum Nanozyme-Loaded Dissolving Microneedles Scavenge ROS and Promote Lineage Progression for Androgenetic Alopecia Treatment Small Methods · 2024