奈米級物理性防曬化?菻~之顯微結構分析、皮膚穿透及細胞毒性之研究

January 2007

吳純佩

nano-sized physical sunscreens titanium dioxide zinc oxide iron oxides nanomaterials skin penetration cytotoxicity hair follicles skin lesions alpha-hydroxy acids stratum corneum desquamation AHAs

TLDR Nano-sized sunscreens may penetrate skin and pose toxicity risks.

This study investigated the microstructural analysis, skin penetration, and cytotoxicity of nano-sized physical sunscreens, specifically focusing on metallic oxides like titanium dioxide, zinc oxide, and iron oxides. The research highlighted concerns that the smaller size of these nanomaterials could increase interactions with biological tissues, potentially leading to toxicological effects if they penetrate the body through hair follicles or skin lesions. The study aimed to develop a technology platform for assessing the characteristics of nanomaterials, which was increasingly important due to their expanding use in cosmetics. However, the experimental data available at the time were not clear or definitive.

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