What is up with Dutasteride making peoples hair loss worse
    9/1/2026

    From the encyclopedia
    Finasteride →

    Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

    Dutasteride →

    5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Finasteride (oral)
    💊 Dutasteride (oral)
    the tone is 😐 neutral.

    Other terms

    Switching from finasteride to dutasteride often causes increased hair shedding initially. Dutasteride is stronger but takes longer to show results, leading to concerns about worsening hair loss during the transition.
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    Related Research

    6 / 6 results

      research Hair characteristics and androgenetic alopecia in Koreans

      8 citations , January 2013 in “Journal of The Korean Medical Association”
      This article reviews factors influencing hair growth and treatment options for androgenetic alopecia, but it reports no new clinical results on their effectiveness.

      research Efficacy of Skin Patting and Iontophoresis with Dutasteride Gel in Male and Menopausal Female Androgenetic Alopecia: A Pilot Study

      September 2025 in “Dermatology and Therapy”
      This pilot study found that using skin patting with iontophoresis to deliver dutasteride gel significantly improved hair density, shaft diameter, and pull test scores in men and postmenopausal women with treatment-resistant androgenetic alopecia, with participants reporting high satisfaction and no adverse events.

      research Male androgenetic alopecia

      January 2025 in “Anais Brasileiros de Dermatologia”
      This review examines male androgenetic alopecia and reports no new clinical results, offering insights to aid dermatologists in making informed therapeutic decisions.

      research Hair Loss in Women

      81 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”
      This review discusses the classifications, diagnostic methods, and treatment strategies for female pattern hair loss, but reports no clinical results.