Verteporfin being used anywhere? 11/3/2022
Verteporfin is being explored for hair regeneration, with unofficial trials and updates shared online. Efforts are being made to encourage more surgeons to trial verteporfin for donor hair regeneration.
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community Random thought that I don't think I have seen here yet. If Verteporfin is able to stop scar formation successfully in humans to a large degree (assuming future studies show this), wouldn't this basically open up the door for it being a no brainer for strong NW2s and 3s to opt for hairline lowering?
The conversation discusses the potential for Verteporfin to reduce scarring, making hairline lowering surgeries more viable for men with mild hair loss. The user suggests that if scarring can be minimized, men might opt for hairline lowering instead of using grafts for other areas.
Related Research
6 / 6 results
research Use of Verteporfin with Dermal Wounding to Regenerate New Hair in Androgenetic Alopecia
In this study, two male patients with androgenetic alopecia who had previously undergone hair transplants showed increased hair regrowth after receiving verteporfin injections, with a 63% mean increase in dense donor sites, 38% in thinning areas, but no growth in bald areas.
research Use of Verteporfin to Regrow Hair and Reduce Fibrosis after Transplantation
In this Stanford study, verteporfin was used to promote scarless skin regeneration by inhibiting YAP activity in a 27-year-old female, resulting in increased hair density at the treated site compared to the untreated control.
research Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling
This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.
research THY1-mediated mechanisms converge to drive YAP activation in skin homeostasis and repair
Targeting THY1 can improve skin repair and healing.
research Dermal Fibrosis and the Current Scope of Hydrogel Strategies for Scarless Wound Healing
This review examines advancements in hydrogel formulations aimed at preventing dermal fibrosis and promoting scarless wound healing, highlighting their role in regulating myofibroblast differentiation and controlling the wound microenvironment.
research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.