How long until pyrilutamide or gt20029 get FDA approved?
Research/Science 5/29/2023

At a glance

In this question or advice post, the primary subjects mentioned are

💧 pyrilutamide (topical)

• GT20029

💧 RU58841 (topical)

the tone is 😐 neutral.

Other terms

androgen receptor DHT androgens topical finasteride finasteride minoxidil androgenic alopecia hair follicles AR signaling pathway Pyri GT RU topical fin fin min

Hair loss treatments pyrilutamide and GT20029 discussed. Pyrilutamide approval in 2 years, GT20029 in 5-6+ years.

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community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

hokq699 in Finasteride/Dutasteride 13 upvotes 2 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community Anyone excited for CosmeRNA coming this month?

throwaway282718 in Product 171 upvotes 1 year ago

CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

HarutoHonzo in Treatment 44 upvotes 8 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community It’s over. NOTHING has worked.

thejaketor in Chat 95 upvotes 2 years ago

A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

HMI115_GIGACHAD in Research/Science 126 upvotes 1 year ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

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