Mechanism of action of alfatradiol (17 alpha estradiol)
Research/Science 5/29/2024
alfatradiol 17 alpha estradiol 5 alpha reductase DHT T androgenic alopecia aromatizes ER-X hypothalamic–pituitary–adrenal axis Luteinizing hormone Leydig cells testicular pituitary antiandrogens Fin Dut Min topical antiandrogens HPA axis LH Finasteride Dutasteride Minoxidil
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
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