Switched from Finasteride to Dutasteride – could the increase in scalp testosterone make hair loss worse 9/29/2026
Switching from finasteride to dutasteride may lead to increased scalp testosterone, which some fear could worsen hair loss despite lower DHT levels. Experiences vary, with some seeing improvement and others experiencing more shedding or worsening hair, suggesting individual sensitivity and the need for patience.
View this post in the Community →
Similar Community Posts Join
6 / 6 resultscommunity 5 years on topical finasteride, 3.5 years on oral minoxidil; now changing from finasteride to dutasteride
A 66-year-old male experienced significant hair regrowth using topical finasteride for 5 years and oral minoxidil for 3.5 years, with no side effects. He is now switching from finasteride to topical dutasteride 0.1% to potentially improve results further.
community Is it possible for topical finasteride to be more effective than dutasteride for some people?
Topical finasteride may be more effective than dutasteride for some individuals, with some users reporting better results with finasteride. Combining finasteride and dutasteride in a topical formula is questioned for its effectiveness.
community Adding dutasteride to fin regimen
The conversation discusses adding dutasteride to a finasteride regimen for potential hair regrowth or thickening. Some users report positive results with the combination, while others caution about side effects like reduced libido.
community Finasteride stopped working. Losing ground on Dutasteride.
The user started with Finasteride at 19, added Dutasteride and Minoxidil at 26, but continues to experience hair loss. Suggestions include checking health markers, considering genetics, and possibly increasing Minoxidil dosage.
community 1.5 years on 1.2 Mg fin. Minimal results. Recently switched to dutasteride.
The user has been on 1.2 mg finasteride for 1.5 years with minimal results and recently switched to dutasteride. Suggestions include adding minoxidil, derma rolling, and considering dietary changes to improve hair health.
community Switching from finasteride to dutasteride
Switching from finasteride to dutasteride may stop further hair loss, but noticeable thickness gains can take over six months. Minoxidil can increase hair density, and microneedling may enhance its effectiveness.
Related Research
6 / 6 resultsresearch The Use of Oral Dutasteride, Minoxidil, and Finasteride for Treating Endocrine Therapy-Induced Hair Loss from Breast Cancer Treatment: A Case Series Study
Oral dutasteride, minoxidil, and finasteride may help reduce hair loss in breast cancer survivors, but more research is needed.
research Review: Dutasteride, fesoterodine, and finasteride are beneficial for lower urinary tract symptoms in older patients
Dutasteride, fesoterodine, and finasteride help older patients with urinary issues.
research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men
In this study, administering 5alpha-reductase inhibitors reduced dihydrotestosterone levels and was associated with mild, reversible decreases in semen parameters in healthy men.
research The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men
This study found that 1-year use of 5alpha-reductase inhibitors, dutasteride or finasteride, significantly lowered dihydrotestosterone levels without adversely affecting bone density, lipids, or hemoglobin in normal men.
research Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride
This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.
research The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis
This meta-analysis found that dutasteride was more effective than finasteride in increasing hair count and improving photographic assessments for men with androgenetic alopecia, while both drugs had similar rates of sexual dysfunction-related adverse effects.