Oral fin -> topical, shedding like hell Finasteride/Dutasteride 4/27/2026
The user experienced severe side effects from oral finasteride, including sexual dysfunction and mental health issues, and switched to topical finasteride, which led to significant hair shedding. They are considering other treatments like RU58841 or topical dutasteride and are advised to check testosterone levels and address potential underlying health issues.
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6 / 6 resultscommunity Finasteride and Topical Minoxidil to Dutasteride and Oral Minoxidil. Is RU58841 still helping?
The user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil, questioning the effectiveness and safety of continuing RU58841. They experienced hair loss improvement initially but are now considering stopping RU58841 due to cost and safety concerns.
community Adding Topical Dutasteride on top of Oral Finasteride & Oral Minoxidil (19m)
The user experienced gradual hair thinning since 2021 and tried various treatments including topical minoxidil, rosemary oil, oral finasteride, oral minoxidil, RU58841, and oral dutasteride. They are considering switching to daily finasteride and adding topical dutasteride, tretinoin, and microneedling due to side effects from oral dutasteride.
community September - december with fin + oral & topical min + ru58841.
The user experienced hair regrowth using finasteride, oral and topical minoxidil, and RU58841, despite initial shedding. They also transitioned from finasteride to dutasteride and addressed scalp issues with a folliculitis shampoo.
community Hair loss still progressing despite finasteride, dutasteride, oral minoxidil, and trying RU58841. What next?
Despite using finasteride, dutasteride, oral minoxidil, and RU58841, hair loss continues to progress. Options considered include increasing dutasteride or minoxidil doses, adding topical treatments, and exploring other potential causes of hair loss.
community Worth it to add topical fin to oral fin?
The user is taking 1mg finasteride daily and RU58841 5% but still experiencing hair loss. They are considering adding topical finasteride or switching to dutasteride, and are not planning to use minoxidil until hair loss stabilizes.
community Combining oral dut with topical finasteride for reduced scalp DHT
The conversation discusses combining oral dutasteride with topical finasteride to further reduce scalp DHT levels for hair regrowth. Users debate the effectiveness and safety of this combination, with some suggesting alternatives like topical antiandrogens such as RU58841, fluridil, and alfatradiol.
Related Research
6 / 6 results
research Anti-androgens for the treatment of hirsutism
This review discusses various anti-androgen treatments for hirsutism, including androgen receptor blockers and inhibitors, and emphasizes the role of diagnosis in selecting the most appropriate therapy, but reports no new clinical results.
research Female Pattern Hair Loss: An Overview with Focus on the Genetics
This review discusses the genetic differences between male and female pattern hair loss and highlights the uncertainty surrounding genetic factors in female pattern hair loss, but reports no clinical results.
research Hair loss and herbs for treatment
This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.
research Comparative Evaluation of the Clinical Efficacy of PRP-Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia
This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.
research The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
This study in rats found that a new hydroxypropyl-β-cyclodextrin formulation of minoxidil reduced the adverse cardiovascular and proliferative effects seen with traditional minoxidil solutions.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.