If apply topical fin goes systemic then does it matter where I apply it on the scalp?
    Finasteride/Dutasteride 5/8/2024

    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 Finasteride (topical) 0.005%
    💧 Minoxidil (topical)
    the tone is 😐 neutral.

    Other terms

    The conversation is about whether topical finasteride and minoxidil need to be applied directly to the affected areas of the scalp or if they can be spread through blood vessels. It also asks how long topical finasteride remains on a pillow.
    View this post in the Community →

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    5 / 5 results

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       1019 upvotes 1 year ago
      The user experienced significant hair growth after using minoxidil 5% and finasteride 1.25mg daily for three months, despite initial shedding. They noted improved hair density, especially at the temples, and plan to manage excess hair growth on the forehead.

      community [26M] Is it time to embrace the bald?

       54 upvotes 4 months ago
      A 26-year-old is considering embracing baldness after mixed results and side effects from using dutasteride, minoxidil, and finasteride for hair loss. Suggestions include trying new hairstyles, considering a hair transplant, or focusing on self-acceptance.

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       292 upvotes 4 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community 4 years of fin+min, 6 months of dut+min progress

       75 upvotes 3 months ago
      The user has been using finasteride and minoxidil for 4 years and switched to dutasteride and minoxidil 6 months ago, but is concerned about lack of progress and hair loss. They have not experienced side effects and are considering other options like blood tests and dosage adjustments.

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      in Minoxidil  178 upvotes 1 year ago
      Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.

    Related Research

    6 / 6 results
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      May 2025 in “Frontiers in Bioengineering and Biotechnology”
      In this study, the researchers reported that a novel exosome-based treatment, EX104, effectively reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, showing results comparable to minoxidil and surpassing it in stimulating capillary growth and follicular proliferation.
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      This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
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      This review discusses the potential of therapeutic antibodies as an alternative treatment for androgenetic alopecia, highlighting the initial development stages and the need for further validation and optimization of targets like the prolactin receptor and Interleukin-6 receptor.