DHT Gel (2.5%) to beard area + Dut + Pyri 1% + Minox
    9/27/2025

    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Pyrilutamide →

    highly targeted anti-androgen that might have minimal systemic effects

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💧 DHT Gel (topical) 2.5% 9 months
    💊 Dutasteride (oral) daily 7 years
    💧 Pyrilutamide (topical) 1%
    💧 Minoxidil (topical)
    the tone is 😐 neutral.

    Other terms

    The conversation discusses using a combination of DHT gel, dutasteride, pyrilutamide, and minoxidil to promote beard growth while minimizing hair loss. Users suggest consulting a doctor and considering genetic factors before proceeding.
    View this post in the Community →

    Similar Community Posts Join

    5 / 5 results

      community Wouldn’t this nuclear stack make it almost impossible to lose hair?

       67 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen involving dutasteride, pyrilutamide, oral minoxidil, and microneedling, with the aim of suppressing DHT and stimulating hair growth. Users debate the effectiveness and potential side effects of these treatments, noting that individual results may vary and that no treatment is foolproof.

      community My DHT levels while being on DUT for a year

      in Finasteride/Dutasteride  33 upvotes 1 year ago
      The conversation discusses the ineffectiveness of tablet forms of dutasteride for hair loss due to poor absorption compared to soft gel capsules. It suggests switching to FDA-approved soft gel capsules for better results, as tablets may not adequately suppress DHT levels.

      community What if Dutasteride doesn't work? Is it the end?

      in Finasteride/Dutasteride  19 upvotes 5 months ago
      Finasteride and Dutasteride are used to block DHT and treat hair loss, but some people don't respond to these treatments. Alternatives include increasing Dutasteride dosage, adding topical finasteride, or exploring other treatments like RU58841, though results vary.

      community Oral Dut/Minoxidil for two years - no results.

       102 upvotes 1 year ago
      The user has used oral Dutasteride and Minoxidil for two years without regrowth, despite trying Finasteride and supplements. They consider increasing Minoxidil, adding microneedling, and switching medications, while others suggest RU58841, a hair transplant, or checking for other hair loss causes.

      community Dutasteride is my last Hope ??

      in Finasteride/Dutasteride  16 upvotes 3 years ago
      User tried topical and oral finasteride and oral minoxidil for hair loss without success. ButterscotchSea3159 suggests using Dutasteride, oral minoxidil, ketoconazole shampoo, microneedling, and possibly RU for better results.

    Related Research

    6 / 6 results

      research Updates in Treatment for Androgenetic Alopecia

      January 2025 in “Annals of Dermatology”
      This review discusses current and emerging treatments for androgenetic alopecia, covering mechanisms, efficacy, and safety of both androgen-targeted and non-androgen-targeted approaches, but reports no new clinical results.

      research Androgenetic Alopecia: Therapy Update

      May 2023 in “Drugs”
      This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.

      research The 100 most cited articles in androgenetic alopecia: A bibliometric analysis

      March 2025 in “Medicine”
      This study performed a bibliometric analysis of the 100 most cited articles on androgenetic alopecia from 1975 to 2024, revealing that U.S. authors contributed most and highlighting a trend toward research focused on treatment options, especially between 2020 and 2024.

      research The Hormonal Background of Hair Loss in Non-Scarring Alopecias

      February 2024 in “Biomedicines”
      This review examines the hormonal causes of hair loss, noting how androgen excess can lead to follicle miniaturization and linking estrogen deficiency and thyroid dysfunction to common alopecia types. It further discusses hormonal treatments such as finasteride, dutasteride, and spironolactone.

      research Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique

      March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)”
      This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.

      research Recent Advances in Drug Development for Hair Loss

      April 2025 in “International Journal of Molecular Sciences”
      This review highlights the limitations of existing hair loss treatments like minoxidil and finasteride and suggests that future therapies may benefit from focusing on antibody and cell-based treatments, which offer targeted and potentially transformative options for managing hair loss disorders.