Anyone stop finasteride or duasteride after 10+ years of use and have no lasting negative effects?
    Finasteride/Dutasteride 10/28/2025

    From the encyclopedia
    Finasteride →

    Prescription tablet (1 mg) that slowed hair loss versus placebo in two-year trials. Labels warn of sexual side effects that have continued after stopping, and of depression and suicidal thoughts; not for use in pregnancy.

    Dutasteride →

    A stronger DHT blocker than finasteride, approved for hair loss only in South Korea and Japan and off-label elsewhere, with the same class of side effects and a much longer washout.

    At a glance
    In this general discussion post, the primary subjects mentioned are
    💊 Finasteride (oral) 10+ years
    💊 Dutasteride (oral) 10+ years
    the tone is 😐 neutral.

    Other terms

    The conversation discusses the potential long-term effects of stopping finasteride after extended use, with differing opinions on the existence and prevalence of post-finasteride syndrome (PFS). Some users report persistent side effects, while others argue that such effects are rare or unrelated to the medication.
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    Related Research

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      research Post-Finasteride Syndrome: An Underestimated Phenomenon

      May 2017 in “Urology and andrology”
      Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.

      research MP89-08 POST-FINASTERIDE SYNDROME: REAL OR IMAGINED?

      2 citations , March 2016 in “The Journal of Urology”
      This study found that the 1 mg dose of finasteride was associated with a wide range of adverse effects, including sexual, psychological, and metabolic symptoms, in the FAERS data.

      research Atypical post-finasteride syndrome: A pharmacological riddle

      8 citations , May 2016 in “Indian Journal of Pharmacology”
      This case report describes an atypical postfinasteride syndrome in a patient treated with both dutasteride and finasteride for androgenic alopecia, highlighting its multisystem involvement and irreversible nature.

      research Post-finasteride syndrome: a surmountable challenge for clinicians

      30 citations , January 2020 in “Fertility and Sterility”
      This review discusses the evidence for post-finasteride syndrome as a condition potentially induced by finasteride and dutasteride, associating them with sexual dysfunction, depression, anxiety, and suicidal ideation in a subset of men, and reports no new clinical results.