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research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Characterization of Xenobiotic Metabolizing Enzymes of a Reconstructed Human Epidermal Model from Adult Hair Follicles

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

research FOXN1 Deficient Nude Severe Combined Immunodeficiency

32 citations, January 2017 in “Orphanet journal of rare diseases”

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

research Clinical And Hemato-Biochemical Studies On Goats Naturally Infested With Sucking And Biting Lice

January 2023 in “Trakia Journal of Sciences”

Goats infested with lice showed anemia and skin issues, which improved after treatment.

research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis

29 citations, July 2014 in “PloS one”

Meis1 is crucial for skin health and tumor development.

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Community Join

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community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 453 upvotes 2 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

community PYRILUTAMIDE KX-826 experience

in Research/Science 98 upvotes 2 years ago

A user's experience with the hair loss treatment Pyrilutamide KX-826, which has resulted in some side effects and shedding. The conversation also includes advice for baseline pictures and trying treatments for at least 6 months.

community Redensyl (The Ordinary Serum)

in Treatment 19 upvotes 4 years ago

Redensyl, a hair loss treatment that has been claimed to be 80% more effective than minoxidil, but users have not experienced any results from using it.