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research Polygenic Control of the Wavy Coat of the NCT Mouse: Involvement of an Intracisternal A Particle Insertional Mutation of the Protease, Serine 53 (Prss53) Gene, and a Modifier Gene

January 2022 in “Mammalian Genome”

The wavy coat in NCT mice is caused by multiple genes, including a mutation in the Prss53 gene.

research The Naked Truth: Sphynx and Devon Rex Cat Breed Mutations in KRT71

75 citations , October 2010 in “Mammalian genome”

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

research Beyond Wavy Hairs: The Role of EGFR in Skin and Hair Biology

160 citations , June 2008 in “American Journal Of Pathology”

EGFR signaling is crucial for skin and hair health, and targeting it could help treat skin diseases and cancer.

research An Autosomal Recessive Nonsense Variant in the EGFR Gene Induces Perinatal Lethality in Blonde d'Aquitaine Calves

January 2026 in “BMC Veterinary Research”

A genetic variant in "Blonde d'Aquitaine" calves causes death at birth due to a missing protein.

research Mutations in the Helix Termination Motif of Mouse Type I IRS Keratin Genes Impair the Assembly of Keratin Intermediate Filament

27 citations , November 2007 in “Genomics”

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

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community Early signs that tell you you have Male Pattern Baldness

in Finasteride/Dutasteride 154 upvotes 5 years ago

Male Pattern Baldness, and identifying early signs of it. The treatments discussed to combat and slow balding include finasteride, dutasteride and minoxidil.

community Dutasteride/finasteride theory

in Finasteride/Dutasteride 5 upvotes 1 year ago

Finasteride worked better for frontal scalp hair loss, while dutasteride helped the crown and mid-scalp but worsened the frontal area. The user shared personal experiences and invited open dialogue.

community Us curly/ wavy hair guys have it worse

in Chat 39 upvotes 1 year ago

Curly and wavy hair can make hair loss appear worse due to clumping, but using less product, shorter cuts, and leave-in conditioner can help manage appearance. Minoxidil and finasteride are considered for treatment, and some find that styling can hide thinning areas.

community 3 years on finasteride update. 23 (left) vs 26 (right)

in Progress Pictures 1316 upvotes 1 year ago

A user shared progress pictures after 3 years on finasteride, showing improved hair thickness and density, and mentioned losing 15kg. The user plans to fix their hairline next month and received mixed feedback on their hairstyle and the effectiveness of finasteride.

community Dry hair vs wet hair, is minox, microneedling and ketoconazole enough?

in Treatment 110 upvotes 2 years ago

The conclusion of the conversation is that using minoxidil, finasteride, and ketoconazole may not be enough to address hair loss caused by DHT. Some users recommend starting finasteride to prevent further hair loss, while others express concerns about potential side effects.

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