2 citations
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November 2017 in “PloS one” This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.
October 2023 in “Journal of Pakistan Association of Dermatologists” This randomized control trial reported that patients with alopecia areata typically have lower serum Vitamin D levels, and treatment with topical vitamin D3 analogue calcipotriol led to significant hair regrowth in 71% of participants over six months.
March 2023 in “Pakistan Journal of Medical & Health Sciences” This study found that alopecia areata patients often had low vitamin D levels, and topical calcipotriol treatment significantly reduced the severity of their hair loss.
January 2024 in “Journal of advanced research in Medical and Health science” This study observed that vitamin D deficiency in alopecia areata correlates inversely with disease severity and duration, but does not correlate with serum vitamin D levels.
In this study, topical and intralesional vitamin D3 and its analogs were found to be effective and safe treatments for mild-to-moderate alopecia areata, achieving a 53.75% success rate, though intralesional vitamin D3 was less effective than other treatments like corticosteroids.