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Rat Hair-Follicle-Associated Pluripotent Stem Cells Can Differentiate Into Atrial or Ventricular Cardiomyocytes in Culture Controlled by Specific Supplementation

research Rat Hair-Follicle-Associated Pluripotent Stem Cells Can Differentiate Into Atrial or Ventricular Cardiomyocytes in Culture Controlled by Specific Supplementation

January 2024 in “PloS one”

Rat hair-follicle stem cells can become heart cells with specific supplements.

research KATP Channels in Zebrafish Cardiovascular System: A Model to Study Cantú Syndrome

February 2020 in “Biophysical journal”

Zebrafish with mutations similar to human Cantú Syndrome have heart cells with altered channel properties, making them a good model to study the condition.

research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction

56 citations , January 2015 in “Circulation”

Finasteride helps reduce heart issues and improves heart function.

research Reduced Plakoglobin Increases the Risk of Sodium Current Defects and Atrial Conduction Abnormalities in Response to Androgenic Anabolic Steroid Abuse

7 citations , February 2024 in “The Journal of Physiology”

Reduced plakoglobin and steroid abuse increase the risk of heart rhythm issues.

research Myocardial NF-κB Activation Is Essential for Zebrafish Heart Regeneration

85 citations , October 2015 in “Proceedings of the National Academy of Sciences of the United States of America”

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

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community Extreme caution: my experience using Ru58841 only once

in Treatment 10 upvotes 11 months ago

An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

community P-1075: a BETTER version of Minoxidil

in Research/Science 2 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community Only thing I regret is not starting sooner. 5 months update

in Progress Pictures 312 upvotes 3 months ago

The user experienced significant hair regrowth and thicker hair after 5 months of using oral Dutasteride and Minoxidil, with no side effects. They regret not starting the treatment sooner and encourage others to try it, noting the ease of obtaining prescriptions online.

community Has anyone ever tried nandrolone to regrow hair?

in Research/Science 2 upvotes 5 months ago

Nandrolone is discussed as a potential treatment for hair regrowth, with some users noting its effectiveness but also its risks, such as organ damage and cardiovascular issues. It is suggested not to be used with finasteride, and some users are experimenting with alternative hormone therapies for hair thickening.

community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

in Research/Science 7 months ago

Blocking DHT is not a complete solution for hair loss; instead, altering the scalp's response to DHT may be more effective. Topical finasteride and minoxidil are current treatments, but future approaches may involve bioengineering, gene therapy, and inflammation control.

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