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Effects of the Biomimetic Peptide Sh-Polypeptide 9 (CG-VEGF) on Cocultures of Human Hair Follicle Dermal Papilla Cells and Microvascular Endothelial Cells

research Effects of the biomimetic peptide Sh-Polypeptide 9 (CG-VEGF) on cocultures of human hair follicle dermal papilla cells and microvascular endothelial cells

7 citations , December 2015 in “Experimental Dermatology”

The study found that Sh-Polypeptide 9, a biomimetic peptide, enhances endothelial tubulogenesis and VEGF production more effectively than minoxidil, particularly at low concentrations, suggesting potential for hair follicle vascularization.

research Topical Rice Bran Oil (Oryza sativa L.) Has The Same Effect With 2% Topical Minoxidil To Prevent Senile Alopecia Through Improved Vascular Endothelial Growth Factor (VEGF) Protein Expression, Hair Follicle Diameter And Length In Wistar Rats (Rattus norvegicus) Exposed To Ultraviolet B Light

January 2023 in “International journal of research publications”

According to this study, rice bran oil was as effective as 2% minoxidil in improving hair growth parameters, such as VEGF expression, follicle diameter, and hair length, in Wistar rats treated for 21 days, showing potential for preventing hair thinning associated with aging.

research Topical Allium cepa Ethanol Extract Restores SOD and VEGF Without Increasing Hair Length in UV-B-Exposed Wistar Rats

May 2026 in “Bioscientia Medicina Journal of Biomedicine and Translational Research”

In this study, topical red onion ethanol extract significantly restored cutaneous antioxidant and pro-angiogenic markers in UV-B-exposed rats, enhancing SOD and VEGF levels dose-dependently, but did not influence hair length, suggesting potential as an adjunct for hair photoaging.

research Rosmarinus officinalis Essential Oil Increases Hair Length and Follicle Diameter of Ultraviolet B-exposed Mice Through VEGF

August 2023 in “The Indonesian Biomedical Journal”

This study on UVB-exposed mice found that topical application of 10% Rosmarinus officinalis essential oil significantly increased hair length and follicle diameter, attributed potentially to its antioxidant compounds.

research Investigation of the Gene Expression Levels of 5 α-reductase, VEGF and IL-1α in HaCaT Cells after the Application of a Botanical Extract

1 citations , January 2014 in “Journal of Dermatology and Venereology”

In this study, a plant extract from Northeastern Turkey demonstrated potential for preventing hair loss by downregulating inflammation and androgen production and promoting hair growth in HaCaT cell models.

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Learn

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learn Vascular Endothelial Growth Factor

How does Vascular Endothelial Growth Factor (VEGF) differ from DHT-blocking treatments for androgenic alopecia? VEGF promotes blood vessel growth, while DHT-blocking treatments reduce hormone effects on hair follicles.
Can products that stimulate Vascular Endothelial Growth Factor (VEGF) improve blood flow to hair follicles? Yes, products that stimulate VEGF may improve blood flow to hair follicles.
What is Vascular Endothelial Growth Factor (VEGF), and how does it support hair growth in alopecia? VEGF promotes hair growth by enhancing blood supply to hair follicles.
All 5 questions on Vascular Endothelial Growth Factor →

learn Thymosin Beta 4

learn Procyanidin

bioflavonoid found in plants with antioxidant and hair stimulating properties

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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Community Join

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community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

135 upvotes 1 year ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community Growth factors, VEGF, And more,possible permanent cure for people with moderate hairloss?

3 upvotes 1 year ago

The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.

community Best, possible, or experimental growth agonists that AREN'T MINOXIDIL.

4 upvotes 5 years ago

Various hair growth treatments were discussed, including microneedling, bimatoprost, setipiprant, stemoxydine, PGE2, CB-03-01, WNT Beta-Catenin upregulators, KY19382, topical estrogen, IGF-1, GH, MK-677, oral castor oil, fisetin, resveratrol, cetrizine, and lactic acid. Users shared experiences and sources for these treatments, with some expressing interest in topical solutions and others noting the lack of FDA approval or scientific evidence for certain options.

community Bee venom better than minoxidil?

in Research/Science 1061 upvotes 9 months ago

Bee venom at 0.001% concentration was more effective than 2% minoxidil in promoting hair growth in mice, possibly due to increased growth factors and reduced inflammation. Caution is advised due to potential allergic reactions and the reliance on animal data.

community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

in Research/Science 13 upvotes 1 year ago

BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

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