47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
April 2026 in “BMC Biotechnology” This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.
April 2025 in “Journal of Pharmacy and Pharmacology” This study reviewed how certain phytochemicals can stimulate hair follicles, promote keratinocyte proliferation, and engage specific signaling pathways like Wnt/β-catenin and AKT, suggesting these natural compounds may offer safer alternatives for promoting hair growth. However, challenges in bioavailability and formulation standardization remain to be addressed.
April 2025 in “ALEXMED ePosters” This study reported that CXCL12 may have a dual role in alopecia areata, where decreased levels could impair angiogenesis and disrupt vascular support to hair follicles, while its overexpression might exacerbate autoimmune attacks on hair follicles, contributing to hair loss.
5 citations
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January 2023 in “Fertility and sterility” This review discusses the emerging considerations and challenges of uterus transplantation for transgender women but presents no new clinical results.