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GlossaryTrypsin

enzyme that digests proteins in the small intestine

Trypsin is an enzyme produced in the pancreas that plays a crucial role in digestion. It breaks down proteins in the small intestine into smaller peptides, making it easier for the body to absorb nutrients. For professionals, it's important to note that trypsin is initially produced as an inactive precursor called trypsinogen, which is then activated in the small intestine.

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research A Randomized Pilot Study to Compare Hair Follicle Cell Suspensions Prepared Using Trypsin Alone Versus Trypsin in Combination with Collagenase Type I for Transplantation in Vitiligo

5 citations, July 2019 in “Clinical and experimental dermatology”

Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.

research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes

2 citations, December 2016 in “Experimental cell research”

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

research Heterotypic Cell Contacts and Basal Lamina Morphology During Hair Follicle Development in the Mouse: A Light, Scanning, and Electron Microscopic Study at the Site of Tissue Interaction

13 citations, December 1983 in “Canadian journal of zoology”

Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.

research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region

5 citations, July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damage hair follicles by detaching stem cells.

research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region

2 citations, July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.

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