1 citations
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December 2022 in “Planta Medica” This study found that adding iontophoresis of papain and chymotrypsin to laser treatment significantly increased hair reduction in women with facial hirsutism compared to laser treatment alone over six months.
March 2026 in “Cosmetics” This study found that combining Alexandrite laser with iontophoresis of chymotrypsin and papain enzymes reduced the laser pulse requirements compared to laser alone for treating paradoxical hypertrichosis in women with facial hirsutism, suggesting potential clinical benefits in managing this condition.
5 citations
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July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The researchers reported that applying proteolytic enzymes to mice skin negatively affected hair follicles, leading to degeneration and potential impairment of stem cells from the bulge area.
2 citations
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July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this study, proteolytic enzymes applied to mice skin caused severe degeneration in hair follicles, including detachment of stem cells from their niche, suggesting potential impairment of stem cell function.
January 2022 in “Annals of Institute of Biology University of Sarajevo” This study reviewed previous research and highlights the potential of plant-derived compounds as anti-coronaviral agents, emphasizing the inhibition of viral enzymes and the need for further natural-origin antiviral investigations.