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GlossaryTrypsin

enzyme that digests proteins in the small intestine

Trypsin is an enzyme produced in the pancreas that plays a crucial role in digestion. It breaks down proteins in the small intestine into smaller peptides, making it easier for the body to absorb nutrients. For professionals, it's important to note that trypsin is initially produced as an inactive precursor called trypsinogen, which is then activated in the small intestine.

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research A Randomized Pilot Study to Compare Hair Follicle Cell Suspensions Prepared Using Trypsin Alone Versus Trypsin in Combination with Collagenase Type I for Transplantation in Vitiligo

5 citations, July 2019 in “Clinical and experimental dermatology”

Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.

research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes

2 citations, December 2016 in “Experimental cell research”

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

research Heterotypic Cell Contacts and Basal Lamina Morphology During Hair Follicle Development in the Mouse: A Light, Scanning, and Electron Microscopic Study at the Site of Tissue Interaction

13 citations, December 1983 in “Canadian journal of zoology”

Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.

research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region

5 citations, July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damage hair follicles by detaching stem cells.

research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region

2 citations, July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.

research Treatment of Androgenetic Alopecia with Autologous CD200 Positive Cell Suspension

January 2023 in “Turk Dermatoloji Dergisi”

Injecting a cell suspension from hair follicles increased hair density in a balding patient.

Liquid Chromatography-Mass Spectrometry Applied to the Identification and Quantification of Animal Hair Fibers in Textile Products

research Liquid Chromatography-Mass Spectrometry Applied to the Identification and Quantification of Animal Hair Fibers in Textile Products

January 2020

Researchers developed a method to identify and measure different animal hair fibers in textiles, successfully distinguishing materials like cashmere from cheaper fibers.

research Enzymatic Digestion of Scalp Hair Follicle Bulge Yields More Stem Keratinocytes Than Explant Isolation

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Using enzymes to break down scalp hair follicles gets more stem cells for skin and hair growth than the old method.

research Juvenile Diabetes Mellitus With Exocrine Pancreatic Insufficiency in a Thai Bangkaew Dog: A Case Report

March 2020 in “The Thai Journal of Veterinary Medicine”

A Thai Bangkaew dog with diabetes and pancreatic issues improved with insulin, enzymes, and vitamins.

research In Vitro Keratin Expression of Hair Cells

2 citations, November 1992 in “Journal of dermatology”

Hair cells grown in a lab showed specific hair proteins.

research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory

22 citations, January 2017 in “Advanced Healthcare Materials”

The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.

research Surgical Therapies for Stable Vitiligo: Non-Cultured Epidermal Cell Suspension Transplantation

January 2019 in “Springer eBooks”

Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.

research Protease Nexin-1 Is Expressed in Human Dermal Papilla Cells and Is Affected by Androgen

March 1998 in “Journal of dermatological science”

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

research The Metabolism of Testosterone by Dermal Papilla Cells Cultured from Scalp Follicles of Men with Androgenetic Alopecia

August 1993 in “Journal of Dermatological Science”

Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.

research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway

137 citations, October 2009 in “The American journal of pathology”

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

research Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

75 citations, August 2011 in “Journal of Investigative Dermatology”

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

research Degradation Of Human Hair By Papain

75 citations, November 1965 in “Textile research journal”

Papain and bisulfite break down human hair by dissolving parts of it.

research Direct Effects of Minoxidil on Epidermal Cells in Culture

63 citations, January 1984 in “Journal of Investigative Dermatology”

Minoxidil promotes hair growth by increasing cell division and DNA synthesis.

Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro

research Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro

58 citations, January 1987 in “Archives of Dermatological Research”

EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.

research Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles

55 citations, April 2017 in “Experimental Dermatology”

The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.

research Johne's And Crohn's: Potential Link And Mycobacterial Hypothesis

53 citations, May 1987 in “The Lancet”

The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.

research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis

48 citations, May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology”

Trichohyalin is also found in the outer layers of normal human skin.

research HaCaT Cell Proliferation Influenced by Melatonin

28 citations, January 2003 in “Skin pharmacology and physiology”

Melatonin affects skin cell growth differently based on how much and how long it's used.

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Related Terms

Research

research A Randomized Pilot Study to Compare Hair Follicle Cell Suspensions Prepared Using Trypsin Alone Versus Trypsin in Combination with Collagenase Type I for Transplantation in Vitiligo

research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes

research Heterotypic Cell Contacts and Basal Lamina Morphology During Hair Follicle Development in the Mouse: A Light, Scanning, and Electron Microscopic Study at the Site of Tissue Interaction

research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region

research The Effect of Proteolytic Enzymes on Hair Follicles of Transgenic Mice Expressing the Lac Z-Protein in Cells of the Bulge Region

research Treatment of Androgenetic Alopecia with Autologous CD200 Positive Cell Suspension

research Liquid Chromatography-Mass Spectrometry Applied to the Identification and Quantification of Animal Hair Fibers in Textile Products

research Enzymatic Digestion of Scalp Hair Follicle Bulge Yields More Stem Keratinocytes Than Explant Isolation

research Juvenile Diabetes Mellitus With Exocrine Pancreatic Insufficiency in a Thai Bangkaew Dog: A Case Report

research In Vitro Keratin Expression of Hair Cells

research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory

research Surgical Therapies for Stable Vitiligo: Non-Cultured Epidermal Cell Suspension Transplantation

research Protease Nexin-1 Is Expressed in Human Dermal Papilla Cells and Is Affected by Androgen

research The Metabolism of Testosterone by Dermal Papilla Cells Cultured from Scalp Follicles of Men with Androgenetic Alopecia

research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway

research Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay

research Degradation Of Human Hair By Papain

research Direct Effects of Minoxidil on Epidermal Cells in Culture

research Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro

research Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles

research Johne's And Crohn's: Potential Link And Mycobacterial Hypothesis

research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis

research HaCaT Cell Proliferation Influenced by Melatonin

research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang

research Structural Features of the Alpha-Type Filaments of the Inner Root Sheath Cells of the Guinea Pig Hair Follicle

research Cultured Nail Keratinocytes Express Hard Keratins Characteristic of Nail and Hair In Vivo

research Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation

research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis

research Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro

research Rapid Preparation of a Noncultured Skin Cell Suspension That Promotes Wound Healing