29 citations
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September 1986 in “Journal of the American Veterinary Medical Association”
This case study diagnosed a cat with pituitary-dependent hyperadrenocorticism, confirmed by specific hormonal tests and post-mortem findings of adrenal hyperplasia and a pituitary adenoma.
This study found that knockout mice lacking intestinal hephaestin are smaller and anemic compared to wild-type, suggesting other mechanisms may compensate for iron absorption.
10 citations
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February 2007 in “Clinical techniques in small animal practice”
This review discusses the etiology and clinical findings of atypical hyperadrenocorticism in dogs due to sex steroid imbalance and explores various treatment options, but reports no new results.
The user is using minoxidil and finasteride to treat hairloss and is concerned about shedding and potential aggressive hairloss. They noticed some regrowth in trichoscopy pictures but are unsure about real-life changes.
The user has tried various treatments for hairloss, including finasteride, dutasteride, RU58841, Pyrilutamide, and several topical growth factors, but continues to experience a receding hairline and thinning. Despite maintaining a healthy lifestyle, the user is unsure why these treatments are ineffective and seeks advice on the underlying cause.
A user is experiencing hairloss and has been using Propecia, minoxidil, Regenepure DR, and dermarolling, with recent improvements on the left temple but worsening on the right. Suggestions include checking for vitamin deficiencies, thyroid issues, and considering dutasteride.
A user is experiencing hair thinning despite using a combination of treatments: dutasteride, oral minoxidil, microneedling, topical tretinoin, and ketoconazole shampoo. They are concerned about potential baldness due to genetics and are considering simplifying their treatment approach.
The user is frustrated with ongoing hairloss despite using treatments like dutasteride, finasteride, and minoxidil, and is considering shaving their head. They are advised to maintain consistency with medication, consider oral minoxidil, and explore hair transplant options.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.
What conditions can a hair transplant treat?Clinics say transplants can treat pattern baldness, long-inactive scarring alopecia and thinning; a transplant only moves hair a person still has, so the cause of the loss has to be diagnosed first.
Alfatradiol: Can it help if my hairloss is linked to DHT?The one randomised trial of topical alfatradiol — in 103 women — found hair thickness and density essentially unchanged after six months, while minoxidil improved both; its authors credited alfatradiol with slowing hair loss rather than regrowing hair. Laboratory work supports a local effect on follicular DHT, but no controlled trial in men appears to have been published.
Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it?Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.
Is clascoterone suitable for both men and women?Clascoterone is not approved for hair loss in either sex — the approved product is a 1% acne cream. The scalp version has completed phase III trials in men with sponsor-reported positive results; in women the only data is a company-reported phase II significant in one subgroup, so use is off-label and investigational for both.