Pituitary-Dependent Hyperadrenocorticism in a Cat

September 1986 in “ Journal of the American Veterinary Medical Association ”

Mark E. Peterson, Pat Steele

pituitary-dependent hyperadrenocorticism truncal hair loss cortisol dexamethasone ACTH adrenocortical hyperplasia pituitary adenoma Cushing's disease hair loss adrenocorticotropic hormone adrenal gland enlargement pituitary tumor

TLDR The cat had a pituitary tumor causing hormone imbalance and related health issues.

A 9-year-old male castrated cat was diagnosed with pituitary-dependent hyperadrenocorticism, presenting symptoms such as polyuria, polyphagia, pendulous abdomen, truncal hair loss, congestive heart failure, and insulin-resistant diabetes mellitus. Diagnostic tests showed inadequate serum cortisol suppression after dexamethasone, exaggerated cortisol responses to ACTH stimulation, and high plasma ACTH levels. Pathological examination revealed bilateral adrenocortical hyperplasia and a pituitary adenoma, confirming the diagnosis.

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