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5 / 204 results![The Role of Lipids in Promoting Hair Growth Through HIF-1 Signaling Pathway](/images/research/96373ea0-1b05-4afd-8880-dd0488e18ce5/small/40504.jpg)
research The Role of Lipids in Promoting Hair Growth Through HIF-1 Signaling Pathway
Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
![The Role of Lipids in Promoting Hair Growth Through HIF-1 Signaling Pathway](/images/research/fb04bd90-a0c0-4bb9-a38f-bae26054b943/small/41371.jpg)
research The Role of Lipids in Promoting Hair Growth Through HIF-1 Signaling Pathway
This study investigates the role of lipids in hair growth, particularly through the HIF-1 signaling pathway. Researchers observed reduced lipid metabolism in the scalp tissues of patients with androgenetic alopecia. Supplementing lipids in culture mediums enhanced hair growth-related gene expression and the proliferation of human dermal papilla cells (DPCs). RNA-sequencing and HIF-1α knockdown experiments identified HIF-1α as a key regulator in lipid-induced upregulation of trichogenic genes. Additionally, in vitro tests with hair follicle organoids showed that lipids promoted the elongation of hair-shaft-like structures. These findings suggest that targeting lipid pathways could be a promising strategy for treating hair loss.
![Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression](/images/research/a26edb69-b18b-424e-bf49-b8ae132ac6bf/small/34735.jpg)
research Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression
Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
![Hypoxia Inducible Factor-1a Promotes Trichogenic Gene Expression in Human Dermal Papilla Cells](/images/research/ce2c6935-8187-49f8-84b0-33024fa0b252/small/16822.jpg)
research Hypoxia Inducible Factor-1a Promotes Trichogenic Gene Expression in Human Dermal Papilla Cells
A protein called HIF-1a helps control hair growth genes and could be targeted to treat hair loss.
![Hypoxia Inducible Factor-1α Promotes Trichogenic Gene Expression in Human Dermal Papilla Cells](/images/research/3b72a800-3aea-40a2-aee8-bbe5231a3517/small/16724.jpg)
research Hypoxia Inducible Factor-1α Promotes Trichogenic Gene Expression in Human Dermal Papilla Cells
HIF-1α is important for hair growth and could be a treatment target for hair loss.
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5 / 8 resultscommunity New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
community [AMA] 5-Month Progress Report: Dutasteride and Oral Minoxidil Results.
Naepo's 5-month progress report detailing their journey of treating male pattern baldness with dutasteride and oral minoxidil, which has already resulted in an encouraging improvement in hair density. Others have responded with appreciation for the thorough report and asked further questions about Naepo's educational background.
community My story: Trying to halt diffuse hair loss for past couple of years but got acute hair fall after quitting minoxidil and finasteride on my dermatologist recommendation
A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.
community My experience with Trichogenics
A user shared their positive experience with Trichogenics for hair restoration, highlighting their unique zigzag hairline technique and personalized attention. They had 1700 follicles transplanted and praised the natural results.
community Got a hair transplant a few days ago and my forehead is so swollen
Swelling after a hair transplant is normal and can be reduced with ice packs, head elevation, and possibly corticosteroids. The user had a no-shave FUE procedure and is using oral finasteride and minoxidil.