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GlossaryKrebs cycle (Tricarboxylic acid cycle)

series of reactions in mitochondria generating cellular energy

The Krebs cycle, also known as the Citric Acid Cycle or TCA cycle, is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins. This cycle takes place in the mitochondria and produces ATP, NADH, and FADH2, which are essential for cellular energy and metabolism.

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research Glucose and Acetate Metabolism by Isolated Sheep Wool Follicles

8 citations, April 1965 in “Archives of biochemistry and biophysics”

Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.

research Integrating Multi-Omics Analyses of Nonomuraea Dietziae to Reveal the Role of Soybean Oil in [(4′-OH)MeLeu]4-CsA Overproduction

1 citations, July 2017 in “Microbial Cell Factories”

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

research Defining Metabolic Flexibility in Hair Follicle Stem Cell Induced Squamous Cell Carcinoma

October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

research The Molecular Mechanism of PCE-DP, a Novel Brightening Active Ingredient

September 2019 in “Journal of Investigative Dermatology”

PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.

research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

47 citations, March 2019 in “Journal of immunology research”

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

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community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 206 upvotes 8 months ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.