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Glossary Retinoic Acid

derivative of Vitamin A used in acne and wrinkle treatment

Retinoic Acid, also known as Tretinoin or ATRA (All-trans Retinoic Acid), is a derivative of Vitamin A that plays a crucial role in cell growth and differentiation. It is commonly used in dermatology to treat acne and reduce wrinkles by promoting the turnover of skin cells and increasing collagen production.

Related Terms

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learn Tretinoin

the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

learn retinol

What’s the difference between retinol and salicylic acid in scalp care and follicle renewal? Retinol promotes skin renewal while salicylic acid targets scalp exfoliation and acne.
Can retinol help enhance the absorption of ingredients like minoxidil or peptides? Retinol may enhance absorption of minoxidil and peptides by modifying skin barrier properties.
How often should retinol scalp treatments be used to see improvement without over-exfoliating? Use retinol scalp treatments 1-2 times a week to avoid over-exfoliation.
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learn retinoic acid

learn Retinyl Palmitate

learn AC Retinol Liposome

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Research

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research Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro

41 citations , January 2007 in “Journal of Korean Medical Science”

This study found that combining minoxidil with all-trans retinoic acid additively promoted hair growth in vitro by activating certain cell survival pathways and reducing apoptosis markers more effectively than minoxidil alone.

research 694 Retinoid induced changes in the fatty acid profile of sebum and its effect on bacterial growth

April 2016 in “Journal of Investigative Dermatology”

This study found that both topical tretinoin and oral isotretinoin altered the free fatty acid profile of sebum in acne patients, affecting bacterial growth differently for S. epidermidis and S. aureus.

research Retinoic acid in the treatment of eruptive vellus hair cysts

28 citations , August 1981 in “Journal of the American Academy of Dermatology”

This article discusses the urgent issue of preserving freedom of choice in dermatology, highlighted by the American Academy of Dermatology, and reports no new research findings.

research DNA Methyltransferases in Malar Melasma and Their Modification by Sunscreen in Combination with 4% Niacinamide, 0.05% Retinoic Acid, or Placebo

20 citations , April 2019 in “BioMed Research International”

This study found that DNA hypermethylation was present in melasma lesions, and treatments with sunscreen, niacinamide, and retinoic acid were associated with decreased methylation and clinical improvement.

research Novel Drugs Targeting Retinoic Acid Receptors

January 2005

This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.

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Community Join

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community Minoxidil works only with Retinoic acid

314 upvotes 1 year ago

Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.

community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid

6 upvotes 1 year ago

Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

community is it okay to use topical min+tret formula?

1 upvotes 5 months ago

Using a topical formula with 5% minoxidil and 0.01% retinoic acid is considered effective, as tretinoin can enhance minoxidil results and improve scalp health.

community Is this solution unnecessarily aggresive?

in Product 2 upvotes 8 months ago

The solution contains minoxidil, finasteride, azelaic acid, caffeine, retinoic acid, and procapil. Users suggest minoxidil with tretinoin and a 5-alpha reductase inhibitor, while dismissing retinoic and azelaic acids as unnecessary.

community Is my hairloss too aggressive to be stopped/reversed ?

5 upvotes 2 years ago

A 19-year-old male has been experiencing aggressive hair loss since age 15/16 and has tried various treatments including topical Minoxidil, microneedling, tretinoin, retinoic acid, stemoxydine, RU58841, and finasteride without success. He recently added oral Minoxidil but continues to experience significant hair thinning and is considering switching to dutasteride.

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