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    GlossaryTherapeutic Target (treatment target)

    specific molecule or pathway involved in disease for treatment

    A therapeutic target, also known as a treatment target, is a specific molecule or pathway in the body that is identified as playing a key role in a disease process. By focusing on this target, researchers and doctors can develop treatments that specifically interfere with the disease mechanism, potentially leading to more effective and precise therapies. For example, in the context of alopecia, a therapeutic target might be a particular protein or gene involved in hair follicle health and growth.

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    Tracking 11 products like 5 DualGen-15 With PG Plus, 28 Minoxidil Serum, 38 Roman Hair Solution Rx, 109 FOLLICS FR07 and 110 FOLLICS FR10 from by companies like MinoxidilMax, Hims, Roman and Minoxidil Express. View all 11 products »

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      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

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      community Verteporfin and Microneedling

      in Treatments 6 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  743 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.