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GlossaryTransgenic Mice (Transgenic Rodents)

mice with altered genomes to study specific gene effects

Transgenic mice, also known as genetically modified mice, are mice that have had their genomes altered through the introduction of foreign DNA. This genetic modification allows researchers to study the effects of specific genes on development, physiology, and disease, making them invaluable tools in biomedical research.

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Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation

research Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation

37 citations, June 2011 in “Journal of Cellular Biochemistry”

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

research The Role of ADAM17 in PCOS Pathogenesis: A Review Paper

February 2024 in “Journal of Health Science and Medical Therapy”

ADAM17 could be a potential target for treating PCOS.

research Editors' Picks

October 2013 in “Journal of Investigative Dermatology”

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

research Animal Models of Psoriasis: Highlights and Drawbacks

53 citations, June 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Animal models help study psoriasis but have limitations and don't fully mimic the human disease.

research Alopecia Areata: Animal Models

69 citations, July 2002 in “Clinical and Experimental Dermatology”

Alopecia areata is influenced by genetics and immune system factors, and better understanding could improve treatments.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.